As we embark on our quest here today, it is important to begin with an additional understanding of Parkinson’s disease, or PD.
PD is best understood as a neurodegenerative disorder that most directly impacts motor coordination and overall tissue health in the brain. The disease is defined by four primary symptoms: balance and posture problems, bradykinesia, rigidity or stiffness, and tremors.
Unfortunately, Parkinson’s is a progressive condition with no known cure, making it similar to Alzheimer’s disease or other common geriatric problems. According to research, causality where PD is concerned is linked to the formation of plaque on neurons as well as some possible mutations to the genetic code and environmental factors such as exposure to toxic chemicals
At present, we understand this only to be a multifactorial problem.
What is well substantiated and common to all cases of Parkinson’s is a degeneration of the dopamine producing neurons. Effectively, the substantia nigra, or the black part of the brain, is the only pigmented region of the brain, and that pigmentation is basically a byproduct of the fact that this area of the brain is something like the brain’s dopamine factory.
Parkinson’s disease appears to be a degeneration of the capacity of this dopamine factory in the brain.
The Endocannabinoid System and Parkinson’s Disease
As we have discussed in other areas, one of the more remarkable theoretical considerations in studying the potential therapeutic possibilities for CBD is the interesting correlation between the conditions for which it is effective and conditions for which there is no known cause. In other words, if we don’t have any idea what causes something, there’s a good chance that CBD can help with it.
Part of this is likely due to the implication of the endocannabinoid system, which is only just now coming under close scrutiny by medical researchers. As we come to understand more and more how this important system of the body functions and is demarcated, we are likely to come to understand more and more about how previously misunderstood conditions may actually function at their core.
Parkinson’s disease is an excellent example.
It would appear as though the endocannabinoid system is intimately intertwined into the pathogenesis of Parkinson’s disease generally speaking. The question looking forward is essentially about whether or not CBD can consistently relieve symptoms associated with Parkinson’s disease.
So far, both anecdotal and formal research suggests that there is a very good chance that this is true. As noted above, this is likely because of the integral role in associated systems involved in the symptomology of Parkinson’s that is played by the endocannabinoid system, as well as CBD’s ability to impact the functionality of that system.
At this point, if the current path of research continues to be substantiated by further new evidence, it would appear as though the endocannabinoid system, and the manipulation thereof, may prove to be the most central and highly effective treatment for Parkinson’s disease, which implies a tremendous role in the future for CBD in these rare but tragic cases.