Connect with us


A Functional Understanding of CBD



As many have come to understand, CBD has various medical uses, and is presently being utilized by an extraordinary huge number of individuals from all levels of society worldwide, each one treating a specific medical condition or health issue.

Below, we will embark on a detailed investigation into How CBD Really Works. We hope you find this both interesting and educational as you move to ascertain how CBD can be of service in your life as a preventative, treatment, and supplement, as so many others have already found.

Cannabidiol (CBD)

Cannabidiol (CBD) is one of the most prominent active compounds in hemp and cannabis. It is differentiated from THC by virtue of the fact that it does not create the same type of drug experience – the “high” – that THC creates. The explanation behind this distinction between the two substances is the way that, while THC straightforwardly collaborates with the CB1 and CB2 receptors in the body, CBD takes after a fairly roundabout approach towards the same receptors, impacting their functioning without completely binding.

Here is the big point: you have cannabinoids in your body all the time. Your body makes them. CBD helps your body use its own cannabinoids more effectively and efficiently.

The Endocannabinoid System and CBD

Sensations in the psyche and physiology are being controlled by cannabinoid receptors.

These are intended to associate with Cannabinoids created in the body. Some examples of sensations under the purview of these receptor reactions include: hunger, state of mind, pain, sensation, and memory. These receptors are fundamentally isolated into two noteworthy classifications named as CB1 and CB2.

While intended to communicate with the regular Endocannabinoids which are normally delivered by the brain inside the human body, they can also react with phyto-cannabinoids like THC and CBD, and others.

The Key Receptors: CB1 and CB2

Both CB1 and CB2 receptors play key roles in regulating the body’s physiology on many levels. While CB2 is a key part of the immune system, CB1 is regularly part of the nervous system and to some extent may likewise be a piece of the kidneys, lungs, or liver. A couple of the normal capacities satisfied by the CB1 receptor incorporate the arrival of neurotransmitters.

These neurotransmitters come in many forms and control much of what and how we feel as brain-owners. However, they are also known to deliver the psychoactive impact that we feel when experiencing the high associated with THC.


CBD and THC differ greatly in terms of both their mode of action in the body and the impact they have on us.

THC is the one that delivers the “high” most associate with smoking pot or otherwise consuming cannabis on a recreational level. And it binds directly with the receptors involved in the endocannabinoid system of the body.

CBD, by contrast, is more involved in prevention, maintenance, and treatment of health. It does not contain any psychoactive properties (ie, does not deliver that same drug “high”), and also does not bind directly with the ECS receptor system.

The method of activity of CBD is varies quite a bit from that of THC as in it isn’t engaged with coordinate incitement of the previously mentioned receptors. The essential effect of CBD is caused on different receptors, for example, Serotonin, Adenosine, and Vanilloid.

For example, the incitement of TRPV-1 receptor by CBD intercedes an assortment of procedures including inflammation, body temperature, and pain recognition. In addition, CBD is known to cause a restraint in the working of FAAH enzyme that straightforwardly follows up on the CB1 receptor and empowers THC to create its psychoactive impact.

Here are several key therapeutic applications:

Anti-anxiety and Anti-Inflammatory Properties. The anti-anxiety or anti-inflammatory effect of CBD is for the most part connected with the actuation of Adenosine receptor. By fortifying adenosine, CBD advances the arrival of dopamine and glutamate neurotransmitters. Procedures like motor control, perception, inspiration, and reward system are related to the arrival of dopamine, while glutamate is engaged with learning, memory arrangement, excitatory signs, and discernment.

CBD and Serotonin. However, these are not every one of the capacities that are satisfied by CBD inside the human body. It is additionally engaged with the incitement of 5-HT1A serotonin receptor that is known to deliver the anti-depressant impact. This receptor is normal to a tremendous scope of different procedures, for example, craving, pain discernment, sickness, anxiety, and fixation systems. Last yet not the slightest, it has additionally been discovered that CBD tends to decrease the expansion of the cancerous cells and bone reabsorption by means of restraint of GPR55 flagging. GPR55 is prevailing inside the brain and has been related with the indispensable procedures like controlling the circulatory strain, tweaking the bone thickness, and keeping the expansion of cancerous cells.

PPARs – atomic receptor. CBD likewise shows as an anti-cancer treatment by actuating PPARs, otherwise called peroxisome proliferator initiated receptors, which are found on the surface of the phone’s core. Initiation of a receptor alluded to as known as PPAR-gamma has a capacity to actuate the relapse of tumors in human lung cancer cell lines. By enacting PPAR-gamma amyloid-beta plaque, which is a key molecule connected to the improvement of Alzheimer’s disease is corrupted. Along these lines, Cannabidiol, might be a valuable solution for treating Alzheimer’s in patients. Qualities that impact procedures, for example, vitality homeostasis, lipid take-up, insulin affectability, and other metabolic capacities are additionally managed by PPAR receptors. For the reason, diabetics may profit by connecting with into CBD-rich treatment.

Inhibiting Reuptake with CBD

Cannabinoids penetrate the cell membrane by attaching to a Fatty Acid Binding Protein. This protein comes with the package in certain lipid molecules. These intracellular molecules also transport Tetrahydrocannabinol (THC) and the brain’s own particular cannabinoids.

These include the Endocannabinoids Anandamide and 2AG. They head to their particular destinations inside the cell. CBD and THC both control receptors on the surface of the mitochondria and also the core of the cell.

Cannabidiol is firmly drawn to three sorts of FABPs, and it additionally battles with our Endocannabinoids, which are unsaturated fats, for a similar transport molecules. Once inside the cell, Anandamide is separated by FAAH (unsaturated fat amide hydrolase) which is a metabolic enzyme.

FAAH is a characteristic piece of the cell’s sub-atomic life cycle. Be that as it may, CBD meddles with this procedure by lessening Anandamide’s entrance to FABP transport molecules, in this way postponing Endocannabinoid’s entrance into the cell.

How Can CBD Work for You?

Research has shown that it is possible to impact the functioning of the ECS, and such a form of treatment has the potential to aid in combating many health issues.

Will such a course of treatment induce a psychoactive “high”?

No. In fact, research has clearly established that proper dosage and administration can produce the desired effects without any such psychoactive consequences. Importantly, not all of the cannabinoids derived from cannabis induce that type of high.

Hence, these compounds have become an intense area of study as potential major treatment solutions for a long list of ailments, including anxiety disorders, mood disorders, Parkinson’s, Huntington’s, multiple sclerosis, neuropathic pain, spinal cord injury, cancer, atherosclerosis, myocardial infarction, hypertension, stroke, glaucoma, osteoporosis, and many more.

There are various ways to consume CBD, include vape oil, tinctures, capsules, ingestible oil, edibles, and topical creams and sprays.

It takes time and experimentation to figure out what’s right for you. But on this site, you will find much helpful information to guide through that process of trial and error and lead you in the right direction so that CBD can be as helpful in maintenance, therapy, and prevention as it has been for so many other millions around the world.

Continue Reading


Benefits of CBD You Must Know



CBD has been with us for hundreds of years, used by ancients as a natural remedy for a lot of common ailments. It is only one of more than a hundred chemical compounds found in the hemp or cannabis plant. CBD-infused products like CBD oil, CBD softgel capsules, CBD cream, and others have become appealing alternatives for people seeking relief.
CBD oil gets extracted from the hemp plant, then diluted with a carrier oil such as hemp seed or coconut oil. It’s fast becoming popular in wellness and health circles as an option in the treatment of chronic pain, anxiety, and other symptoms brought about by certain disorders.
The benefits of CBD
Because of CBD’s vast variety and reach, it’s used in various mediums of treatment. Like any other medication introduced to the body, your body needs time for adjustment. CBD can help with symptoms but don’t expect overnight results.
It’s generally recommended to use CBD between 30 to 60 days before witnessing any significant impact. If you decide to try CBD, here are some benefits to look forward to:
• Pain relief
Research has shown that CBD has analgesic properties. This means it’s effective for pain relief. When introduced into the body, CBD can impact the endocannabinoid system’s receptor activity resulting in the reduction of inflammation and the interaction with neurotransmitters.

• Stress relief
In this modern age, many people have experienced feeling overworked or over-booked and this affects their abilities to prioritize through the chaos. In simpler words, they feel stressed.

This is where CBD oil can help as using it can ease the anxieties and worries of everyday life. When used, CBD can calm the nerves which, in turn, allows us to focus more on the tasks at hand.

• Improve sleep
CBD may support our need for a deeper and more restful sleep by reducing chronic anxiety, pain, and the other challenges which prevent us from falling into a deep sleep. Its use can diminish REM sleep disorder too. REM during deep sleep paralyzes the body. This inhibits physical reactions to dreams.

• May help reduce depression and anxiety
Two of the most common mental health problems plaguing the world today are depression and anxiety, both of which can have a devastating impact on one’s health and well-being. Many have attested that the use of CBD oil as effective in the treatment of these disorders. Many are now showing interest in CBD as a natural approach to get back a semblance of normalcy in their lives.

CBD also has anti-depressant properties and these have been linked to its ability to act on the brain’s serotonin receptors, a neurotransmitter compound that regulates social behavior and mood.

• Improve the health of your skin
Today, we find so many lotions, body butter, and hydrating products available in drugstores but are these the right products to reach the moisture levels the body thirsts for? Maybe, but a sure option that can quench such thirst is CBD oil or CBD cream. This is a powerful topical which can help the skin maintain optimal skin moisture.

• It’s non-addictive
Another great quality of CBD is that it’s non-addictive. This means you can keep using the same dose in your treatment without worrying about feeling craving for more. As a matter of fact, the more you use it, the better the results. The body doesn’t build up a tolerance to CBD.
Speak with your doctor about using CBD
There’s continuing research on CBD’s potential role in alleviating pain and other symptoms of common health issues. It might even end up as a natural alternative in the treatment of pain. As research goes on, expect the discovery of new therapeutic and medical uses for this compound.
There’s much more to discover about the safety and efficacy of CBD products. But based on the most recent studies, it’s suggested that CBD may provide a powerful and safe treatment for several prevailing health issues. This is especially true if you purchase your CBD products from high-quality manufacturers like Greenleaf Farms.

Continue Reading


What Works Best for Treating Pain with CBD Tincture, Soft gels or Creams? #CBD Tincture #Best All Organic CBD Cream



Cannabidiol (CBD) products such as oils and topicals have become a popular natural remedy for pain. While research is still underway, first-person accounts of the benefits are taking the world by storm.

New products are popping up in every direction you look from CBD oil and CBD tinctures to CBD cream and CBD soft gel capsules. So, no matter your preference, there is a form of CBD to help you treat your pain. Treating pain and inflammation is part of the many benefits that CBD offers the user. Let’s take a deeper look into CBD and pain:

What is CBD and will it make me high?

Many people are skeptical of using CBD as a remedy because of the connotations that come with using a compound that comes from the cannabis or hemp plant. In fact, CBD is the non-intoxicating compound of the cannabis plant and will not make you ‘high’ as if you were smoking marijuana.

The more well-known compound of the plant, THC (tetrahydrocannabinol) is what creates the high. Some CBD oils carry trace amounts (less than 0.3%) of THC. However, oils derived from hemp rather than cannabis do not contain any THC and these are legal in all 50 states across the USA.

How CBD works to reduce pain

When it comes to CBD and pain, this affects the endocannabinoid system in the human body. The endocannabinoid system creates endocannabinoids (its own cannabinoids). The system receives and translates signals from the endocannabinoids and any cannabinoids from CBD products throughout the body.

The endocannabinoid system regulates a variety of functions in the human body. These include immune system responses, sleep and most notably, pain. While CBD does not directly affect the endocannabinoid system according to available research, it does initiate the activation or inhibitions of certain compounds in the body.

CBD in the body can cause a reduction in the absorption of anandamide, a neurotransmitter that helps to regulate pain. Thus, CBD will cause the body to absorb less anandamide, increasing levels in the bloodstream, leading to relief from pain.

The effects of CBD on inflammation to treat pain

Inflammation is the body’s protective response against harmful stimuli. Inflammation is often accompanied by pain, redness and swelling. By treating the cause of the inflammation, you can relieve the pain you might be feeling.

This is one of the most popular ways that CBD is being used as a natural alternative remedy. Since inflammation is one of the body’s immune responses, it is regulated by the endocannabinoid system. So, once again, CBD interacts with neuroreceptors in the body to deliver an anti-inflammatory effect.

By reducing areas of inflammation in the body, CBD can, therefore, help to relieve the pain caused by inflammation. Sometimes the body triggers inflammation when there is no harm done to the body, such as in the case of many autoimmune diseases. CBD oil can greatly help remedy the symptoms of these diseases.

Finding quality CBD products

When using CBD products to relieve pain, you want to find a high-quality CBD product. Be sure to check the details of the oil, tincture or topical that you intend to buy. You want to look for information such as the THC percentage and ensure it is a hemp-derived CBD (especially if you live in a state that has not yet legalized marijuana).

Purchasing your CBD products from a trusted supplier like Greenleaf Farms will ensure that you are receiving a high-quality product. Their hemp is grown under the perfect conditions with no pesticides or herbicides used.

When purchasing from a trusted supplier, it generally comes with the guarantee that you are receiving a pure and authentic CBD to treat and relieve your pain and inflammation. You can also rest easy knowing that your CBD product has been produced with care and your health in mind.

Continue Reading


CBD and Depression Treatments



Harvested from the marijuana plant, cannabidiol (CBD) is extracted from the leaves after harvesting. Although marijuana is known for its mood-altering components, CBD is not one of them. The THC (tetrahydrocannabinol) in cannabis is the main compound in marijuana that causes this effect.

CBD products have minimal traces of THC in them, so there is no chance that this compound can have any adverse effects on the user. The legal requirement is that CBD must contain 0.3% or less THC. Producers who don’t comply risk having their product seized and growing license revoked. The tiny amounts of THC mean that CBD cannot cause the stereotypical high that most people associate with marijuana use.

There are several CBD products the user can choose from, including CBD oil, CBD ointment, and CBD tincture. The conditions it is used for prescribes how CBD should be ingested. Greenleaf Farms’ products come in a large range designed to suit the needs of any user.

As more and more people turn to CBD as an alternative remedy, the list of conditions for which it is recommended is growing. Among them is CBD and depression.

Is there a connection between CBD and depression support?

Depression is caused by a chemical imbalance in the brain. The neurotransmitters that are responsible for communication between the brain and the rest of the body are out of sync. The neurotransmitter most associated with depressive disorders is serotonin.

CBD has been shown through studies to interact positively with the serotonin neuroreceptors in the brain. This helps to maintain healthy serotonin levels.

Serotonin is essential for a feeling of well-being. It can govern a person’s emotional state. An imbalance can cause havoc on a person’s emotional and physical health.

Most people with depression have to take antidepressant medication. The most common antidepressant is fluoxetine, which people may know by the name Prozac. Prozac is an SSRI (Selective Serotonin Reabsorption Inhibitor). The drug prevents the body from losing serotonin through reabsorption into the body. This function allows SSRIs to help maintain steady serotonin levels in the brain of the user.

Other neurotransmitters targeted by certain antidepressants are noradrenaline and dopamine. When an SSRI doesn’t produce the desired result, a doctor will prescribe these drugs to a patient.

The side effect debate

While pharmaceutical drugs might be helpful to a depression sufferer, they have a lot of side effects. These include:

  • A notable increase or decrease in appetite
  • Weight gain or loss
  • Changes in sleep patterns
  • Mood swings
  • Sexual dysfunction such as a loss of the libido

In addition to these side effects, antidepressants may have the opposite effect of that which is desired. This can lead to deepening depression, thoughts, and acts of self-harm, suicidal ideation, and the act of suicide itself.

Another serious implication of taking antidepressants is that some of them are habit-forming. The patient develops a dependence on them, which may be hard to quit.

While CBD has its own side effects, many users report that they are less severe than those of antidepressants. The side effects of CBD are similar to those of most antidepressant medication.

Is there a real possibility that CBC can help patients with depression?

While CBD has been shown in animal studies to have an antidepressant-like effect on its subjects, it is by no means an antidepressant. Scientists are still studying how it works. However, what has been discovered to date bodes well for CBD as a potential treatment for depression.

As a natural remedy, CBD is easier for the body to process, unlike prescription drugs. People who favor a more organic approach to treatment are turning to CBD in the hopes that it will reduce or eliminate the need for antidepressants.

People in treatment should NEVER abandon the medication regime their doctor has prescribed. Doing so can pose a severe threat to their future well-being. An alternative such as CBD oil should always be discussed with a medical professional before implementing its use.


Continue Reading

Trending Stories