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CBD Treatment Case: Rheumatoid Arthritis



Rheumatoid arthritis is a condition marked by something akin to friendly fire when it war – it is essentially an example of your immune system attacking your own body. This condition impacts the heart, skin, eyes, joints, and other systems. Ultimately, it is caused by rheumatism, an autoimmune disease where healthy joint tissue is perceived as a pathogen or foreign body.

The immune system then attacks the body degrading the synovial sac, where the lubricants to keep the joints working well reside.

Understanding rheumatoid arthritis

Rheumatoid arthritis, often referred to as RA, is, as noted above, an autoimmune disorder of the joints. In essence, it’s the immune system attacking normal joint tissue after misidentifying it as a pathogen. Because of this character, the disease is extremely difficult to treat.

Recent data suggests that well over 45 million people 19 years of age or older had been diagnosed and were dealing with osteoarthritis or rheumatoid arthritis by 2009.

Causality and Treatment

Rheumatoid arthritis, as a process, is set in motion when the immune system becomes inflamed and the tax the fluid sacs that lubricate the joints of the body. The inflammation associated with this process prevents the fluid from lubricating the joints, which causes the joints to break down in a manner that is highly painful to those suffering from the disease.

As this process continues, the cartilage and bone within the joint are gradually grounded to nothing. Some of the destroyed tissue becomes scar tissue, which deforms the joint and further immobilizes the individual suffering from this terrible disease.

While there are many components of the immune system, in this case two of them are most central to the process – T-cells and B-cells.

T-cells are in charge of recognizing the enemy, and B-cells are in charge of attacking it. In rheumatoid arthritis, the T-cells failed to properly distinguish, and mark out the synovial fluid sacs as the enemy.

Diagnosis generally happens for rheumatoid arthritis by a physician. That process is really about ruling out other possibilities. The very early stages of this disease are very difficult to mark out for diagnosis. However, once the disease progresses, it is often very easy to diagnose.

There are four essential tests to verify rheumatoid arthritis: Red Blood Cell Sedimentation Rate, C-Reactive Protein Test, MRI, and X-Ray. Current treatment options and best practices for rheumatoid arthritis vary by severity, but the most common methods of treatment are NSAIDS, Steroids, Therapy, Lifestyle Choices such as heat and cold packs and more regular exercise, and Surgery.

Unfortunately, we don’t yet know the exact cause of rheumatoid arthritis.

CBD and Rheumatoid Arthritis

However, the endocannabinoid system has actually been shown to play a big role, and could be a very important tool in fighting back.

As we have noted in other pieces, the endocannabinoid system is a major regulatory network that inhabits the entire body and plays a massive role in many different systems and functions in human physiology.

Crucially, one of its most important functions is being the principal control mechanism involved in the day-to-day management of the immune system.

It is also important to note that the endocannabinoid system is often found to be functioning abnormally in almost all cases of autoimmune disease. In the case of rheumatoid arthritis, cannabinoid receptors fail to properly regulate the immune system cells in terms of their healthy activity, and we see a breakdown in their responsibilities that leads to the symptoms of the disease.

So far, we’ve seen research and anecdotal evidence that suggests that impacting the endocannabinoid system could possibly be a primary route to treating or managing rheumatoid arthritis.

Using CBD for inflammation is a strong possible application that’s directly relevant to rheumatoid arthritis. In fact, one important study involving mice concluded that CBD reduced inflammation and pain as well as the quantity of secretions of inflammatory and bone degrading molecules.

This suggests that CBD oil may possibly be an incredibly important tool in the battle faced by those suffering from rheumatoid arthritis.

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CannTrust Holdings Inc (NYSE:CTST) Penetrates Into The United States After Investing $20 Million



CannTrust Holdings Inc (NYSE:CTST), a Canadian company that produces and sells medical and recreational marijuana has announced the expansion of its business into the United States.

The Canadian firm revealed that it signed a Letter of Intent through which it will start working with Elk Grove Farming Company, LLC to access more than 3,000 hemp production acres in California. The two companies struck a joint partnership that will allow CannTrust to secure a footing in the California market which is one of the biggest cannabis markets in the U.S.

“This agreement represents another bold move for CannTrust. Our U.S. operation is expected to deliver a significant increase in low-cost production capacity,” stated CannTrust CEO Peter Aceto.

CannTrust is financially ready to tap into the U.S market

The CannTrust CEO also noted that the company will take advantage of its experience in the formulation of standardized CBD products as part of its strategy to enter the U.S market. Mr. Aceto also revealed that his company’s successful equity offering provided enough financial muscle to fuel its ambitious expansion plans.

CannTrust aims to be among the leading and trusted suppliers of high-quality, standardized CBD formulations derived from hemp. The company believes that there will be an increasing demand for high-grade CBD formulations from international retailers. It therefore makes sense to invest in processes that will add value to the end product such as genetic studies and expert growing practices to achieve the highest safety and quality standards.

Elk Grove and CannTrust will each have 50% ownership in their joint operations. Elk Grove is an ideal partner for the endeavor because it has years of farming experience in a variety of products. Its focus includes products designed for crop protection, supply, and input. Its operations are distributed across California, which means that the groundwork has already been laid for the partnership. It will thus be easier for the CannTrust to penetrate into the California market.

Elk Grove executive Morgan Houchin stated that his company was excited about the partnership with CannTrust. He added that his firm’s experience in farming operations will be a great combination with CannTrust’s experience in creating class-leading formulations.

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Rocky Mountain High Brands Inc (OTCMKTS:RMHB) Strikes Broker Deal With Carlin Group



Lifestyle brand management firm Rocky Mountain High Brands Inc (OTCMKTS:RMHB) announced on Wednesday that it secured a broker deal with Carlin Group for its products in the retail space.

The broker agreement will allow Carlin to represent RMHB’s CBD-infused drinks through the HEMPd brand. It will also represent beverages infused with Hempseed extract under RMHB brands. The deal will also cover CBD-infused wellness products such as lotions, water-soluble solutions, capsules, gummies and tinctures as part of the HEMPd brand. Spirit Water will also be covered under the agreement.

The RMHB-Carlin broker deal covers multiple states. They include Missouri, Nebraska, Texas, South Dakota, North Dakota, Minnesota, Wisconsin, Illinois, Pennsylvania, Tennessee, Kentucky, Ohio, Indiana, and Michigan.

“We are very excited about the opportunity to have our entire product line represented by Carlin Group,” stated RMHB CEO Michael Welch.

The Carlin broker deal will boost RMHB’s exposure

Welch noted that the broker deal will strategically allow RMHB to leverage optimal exposure to mass marketers, grocery store chains, convenient stores, major retailers and other types of outlets. The company would not have managed to reach such a wide range of outlets cost-effectively without a broker deal.

The RMHB CEO also added that his company and Carlin will maintain a close collaboration so that they can facilitate retail availability of RMHB products. Welch also revealed that RMHB reviewed numerous other retail introduction options. This was before settling on Carlin which the company believes is the best-suited brand to rapidly get its products onto retail shelves.

Carlin Group’s Managing Director Albert Vergilio noted in a statement that his company was excited to host RMHB and the CBD-based products that are part of its HEMPd brand in Carlin’s new CBD division. He also added that it is part of investing in the future of CBD considering the fast-tracked popularity of CBD products, and the regulations that govern them.

Carlin’s sales team will undergo some training to get them acquainted with RMBH’s products. The sales team will then hold meetings with corporate customers as part of the retail rollout of the products. Sales that will be part of the broker deal are expected to kick off in Q3.

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Wildflower Brands Inc (OTCMKTS:WLDFF) Establishes Footprint Across The US With PO For Hemp CBD Products From Dillard’s Department Stores And Eyes Markets In Texas And Florida



Wildflower Brands Inc (OTCMKTS:WLDFF) has announced establishing a nationwide presence with a PO from Dillard’s Department store. The company has fulfilled the PO received from Dillard.

Hemp CBD products in 292 locations

Dillard’s department store will showcase the premium hemp CBD products of Wildflower in its 292 locations across the US. With its best practices and transparency, Wildflower is eyeing the key markets in Texas and Florida. The company will educate the customers in these regions about salable products. Wildflower has received subsequent orders from Dillard’s and is fulfilling the requirements.

Chief Executive Officer of Wildflower, William Maclean said the supply of CBD infused products to Dillard’s Department stores doubles the existing retail locations in the nation. The company aims to capitalize on its brand to become a household name. It will improve loyalty building because of the reputation and respect of Dillard’s as a retailer. Wildflower aims to provide health and wellness benefits of its CBD infused products to the customers in the US through Dillard’s.

Signs a deal with Highmark Interactive

Wildflower has signed a deal to use EQ – Brain Tracking, mobile software of Highmark Interactive, in the clinical research to study the functional neurological and cognitive effects of CBD. The company aims to get meaningful results and data that help to understand the functional and cognitive neurological properties of the cannabinoids.

William said the company would collect testimonials from the customers on its products that provide the health and wellness needs using plant-based solutions. The company will strive to improve the products, and the research helps it to reach that goal and growth with continued investments.

Acquires City Cannabis Corp

Wildflower has signed an LOI on April 3, 2019, to take over City Cannabis Corp. The company will issue its 60 million common shares for the takeover. The companies will complete the acquisition on receiving advice from corporate, tax, and securities law departments.

The cannabis retailer City Cannabis holds two licenses in the City of Vancouver to market cannabis. It is generating profits through operating dispensaries in Vancouver. The acquisition helps Wildflower to expand retail footprint using the expertise of City Cannabis.

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