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CBD CONDITIONS & TREATMENTS

CBD Treatment of ALS

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Amyotrophic lateral sclerosis, or ALS for short, is a tragic disease defined by a neurodegenerative pathogenesis centering on the destruction of motor neurons associated in the motor cortex with voluntary movement, and an associated atrophy of the muscles controlled by those neurons.

Many people know this disease as Lou Gehrig’s disease. It affects a very small portion of the population but has become notorious because of both the story of Lou Gehrig and that of genius theoretical physicist Stephen Hawking, who, by the time he recently passed away, lived nearly 10 times as long as he was supposed to.

Essentially, ALS is about the death of motor neurons in the brain and spine. Once initial symptoms are seen, an individual generally experiences complete physical paralysis within just a couple of years. Since symptoms are only shown after over 30% of the motor neurons have already died, it is basically impossible to catch the disease early.

We don’t really know what causes the disease at this time, and there is no known treatment.

CBD and ALS

One of the interesting things we find as we examine the various and sundry conditions most effectively addressed and treated by CBD is a remarkable correlation with a lack of understanding where causality is concerned. In other words if it’s a tragic health condition that has a completely unknown cause, it seems, by the magic of the universe, to be particularly suited to treatment or therapy through application of cannabidiol, or CBD.

ALS is a particularly good example of this phenomenon. There is only one prescribed treatment of ALS – a glutamate receptor inhibitor known as Riluzole. This medication is meant to decrease the rate at which neurons combine with glutamate. This can prevent some of the excitotoxicity, but is far from a cure.

However, CBD has shown some promise in working to slow several of the drivers of the progression of ALS including excitotoxicity, neuroinflammation, and oxidative stress. In addition, as mentioned in other spots, CBD also works as a palliative and a treatment for some of the psychological stressors that accompany the more direct physiological symptomology associated with ALS.

In other words, it can function as a mechanical inhibitor – at least, we believe at present – and also work to mask some of the more dramatic immediately experienced symptomology. This makes it another case where CBD is somewhat of a double whammy solution, which is one of the reasons why this substance seems to be so dramatically interesting to cutting-edge research currently being entertained on the frontier of medical science.

It is thought that one of the central reasons why CBD can be effective in terms of the mechanical drivers of the cell death associated with ALS is because of the relationship between CB2 receptors and microglial cells in the brain.

These cells function as effectively the immune system of the brain. This is necessary because typical immune related cells are not allowed past the blood brain barrier that separates this important system of the body.

Since CBD agonizes the CB2 receptors, it is able to reduce the death of healthy neurons based on activation of neurotoxic mediators. Importantly, as we understand it now, this active pathway can be affected without compromise of immunity more generally.

This is extraordinarily promising, and we expect further research to ensue to confirm and extend these conclusions, and possibly push CBD to the forefront of the treatment horizon as we continue to search for new strategies to battle ALS.

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The Effects of CBD and Glaucoma

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facts about CBD and Glaucoma

As we discussed the variety of different health conditions that appear to be treatable or preventable through the use of CBD, we must admit to the existence of a spectrum of efficacy. In other words while it appears to have an enormous range of application, there are certain things that it works even better for than others.

One of the best of the bunch is glaucoma.

As the reader is likely aware, glaucoma is a defect with implications for severe damage to an individual’s optic nerve, and thus a failure in the proper functionality of the eye.

Coming to Terms with Glaucoma

While we don’t understand exactly how it’s cause, the most relevant source of serious long-term damage to the optic nerve in cases of glaucoma appears to be hypertension on an intraocular level. In other words,, comes from too much pressure inside of the eye because of too much fluid in between the iris and cornea.

How prevalent is glaucoma? About 2 million suffer from it just in the US. Most of them are around 50 years of age or older by the time we actually see signs of the glaucoma.

The early stage symptomology is relatively inconspicuous. The first thing you deal with in a case of glaucoma’s difficulty seeing out to your periphery – otherwise known as a loss of peripheral vision. If this happens to you, unfortunately I have some bad news: glaucoma is already irreversible at this stage.

This is when we know that there’s already too much pressure directly in the eye and damage is already been done to the optic nerve.

While we don’t fully understand exactly why or how this happens from the outset, the consequences are undeniable.

Here’s how it breaks down: the eye produces something called aqueous humor. No, that’s not a comedy club for fish. It’s actually a fluid it’s meant to sit between the iris and cornea of the eye. But when there’s too much of it, it results in pressure that can damage the optic nerve. It’s also important to understand that this is a very sensitive system.

The optic nerve is actually a highly delicate grouping of nerve tissue and it’s easily damaged. It is a highly delicate instrument. Any alteration leads to irreversible issues with vision.

Can CBD Help?

As we have described, glaucoma is the result of a failure to regulate some delicate balance of some kind of substance somewhere in the body – in this case, the aqueous humor in the eye. What we want to highlight here is that this is a regulatory issue.

While CBD is still on the frontier of its important research development, one thing we have learned for certain at this point is this: CBD is great at regulatory problems.

Why? Because CBD impacts the endocannabinoid system, and the endocannabinoid system is intimately tied into most of the body’s major regulatory systems.

That’s why it’s so good at helping with immune system issues, inflammation issues, pain management, and hormonal balance. These are all important regulatory functions in the body, and ones that the endocannabinoid system is intimately integrated within.

As such, anecdotal and formal research has shown CBD could be a highly valuable tool in the battle against glaucoma. While more research needs to be conducted, we already know that it’s effective, and we already have a pretty good idea why.

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BENEFITS OF CBD

Treatment Option for CBD and Sickle Cell Anemia

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Did you know that scientists aren’t even sure how many people are affected by sickle cell anemia in the world right now? Most people don’t realize that one of the most frequently identified hereditary conditions is in fact sickle cell anemia.

While we don’t know exactly how many people suffer from this difficult condition, we do know that it’s at least millions. Those living in Southwest Asia, the Mediterranean countries, Africa, and India are most at risk.

Coming to Grips with Sickle Cell Anemia

Sickle cell anemia is a common version of the sickle cell disease, as you might guess. The most important and peculiar characteristic that defines this disease is a crescent shape found in red blood cells.

A red blood cell isn’t supposed to be crescent-shaped. Instead, it supposed to be round and flattish, allowing transportation through membranes with tight gaps, which are common throughout the body’s circulatory system.

It is this crescent-shaped or sickle shaped character as well as a rigidity that is responsible for all of the problems that go along with sickle cell disease.

What Causes Sickle Cell Disease?

The cause of sickle cell disease is a gene mutation. Specifically, it is the gene that responsible for hemoglobin production.

Hemoglobin, an important protein found in red blood cells, attaches itself to oxygen molecules to help transport them around the body.

The mutation that causes sickle cell disease is a mutation involved in the production of the shape of red blood cells, resulting in the misshapen, rigid, sickle shaped design that is responsible for the problems that come with this difficult condition.

At the end of the day, the problem that is found with this condition is that of factors involved in causing a difficulty adjusting when the weather is cold, some occasional bouts of dizziness, and a lack of energy.

Diagnosis is actually extremely easy, and most cases of the disease are already detected by the time the baby is born. That said, to know for sure, a doctor will prescribe a blood test diagnosis that will determine precisely whether or not the patient carries the sickle cell abnormality and thus will suffer from effects associated with the disease.

A Solution and a Problem

If you understand more about sickle cell disease, it may not be too surprising to know that case density is greatest in areas where prevalence of malaria is to be found.

You see, the odd shape of red blood cells for individuals with sickle cell disease actually works to repel the spread of malaria throughout the body. Hence, over an even illusionary timeline, sickle cell disease has actually evolved as a defense in areas where malaria is particularly common in individuals are likely to be exposed to it.

In such places, having sickle cell disease actually decreases one’s chances of death, thereby increasing one’s chances of survival and eventual reproduction. This is why the disease has gained traction in certain areas of the world.

How Can CBD Help?

While there are no absolute treatments for sickle cell disease, cannabis and CBD have appeared to make a positive difference in both coping and managing the process that one must endure as a sufferer of sickle cell anemia.

CBD works to aid in the functionality of the immune system as well is the nervous system, thus treating many of the symptoms that are most often experienced by those with this terrible disease.

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BENEFITS OF CBD

Important New Tool CBD Migraines

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facts-about-CBD-Migraine

There can be no doubt about it: headaches are a real headache. For those that suffer from migraines, headaches can be hell.

It’s important for people to understand that migraines represent a special form of headache that constitutes a major health problem. Migraine headaches can be so severe that they can bring about suicidal thoughts for those who suffer from them chronically. But, for such unfortunate individuals, we do have some good news: there is a new weapon in the fight against migraine headaches – CBD.

Migraines, and the Search for a Cure

Any attempt to fully understand the migraine health issue and it’s possible treatment options must start with the following fact: migraine headaches have no known cure.

Certainly, there are many treatments out there that claim to provide some relief for a chronic migraine headache problem. But none have been shown to truly stop the problem from being a part of life for those who suffer from this terrible condition.

Some of the tools offered to us by the pharmaceutical industry to treat migraine headaches include trazodone, propranolol, L-5HTP, flunarizine, nimodipine, and papaverine. However, once again, none represents a cure, and many have important and life-changing side effects included in the package.

However, the good news is that CBD has begun to offer a new ray of hope in this battle. Recent research suggests a strong potential for cannabis and cannabis related substances to provide important measures of relief for those suffering chronically for migraine headaches.

For example, recent research in the journal ‘Pharmacotherapy’ suggests that scientists are starting to build the case that the frequency and intensity of headaches for chronic migraine sufferers can be powerfully impacted by CBD.

Survey Evidence Could Point the Way

In addition, other studies can also be of important note. Unfortunately, one important study did not particularly isolate CBD but may still help to make the case for the impact that CBD can have as a tool for those suffering from this difficult condition.

In fact, in this case, it is an important survey. Assembled by SFGate, the survey was comprehensive and stated clearly that 100% of individuals who responded stated that CBD oil sharply diminished the intensity and frequency of their headaches.

As you may be aware, CBD is perhaps the most important of the cannabinoids, and has zero psychoactive impact. According to historical research, use of CBD for headaches dates back to the Roman Empire, over 2000 years ago.

There is firm evidence to suggest that CBD represents a valuable tool in the fight against migraine headaches. More research is needed to confirm this hypothesis in a manner that is sufficiently convincing for the medical and scientific establishment. But for patients and consumers in the world today suffering from this terrible condition, know that history and anecdotal evidence makes one crystal clear case: that CBD is a tool with tremendous potency and promise.

One should expect the drift of research to land on the same conclusion over time.

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