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BENEFITS OF CBD

The Endocannabinoid System and Neurogenesis

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It is remarkable how society’s collective knowledge moves forward with the passage of time and the production of valuable scientific research. For example, scientists used to believe that all neurogenesis occurred during the gestation of pregnancy.

Naturally, we have begun to understand that that was a misconception, which has led to the establishment of neurogenesis as an important and emerging scientific discipline.

Understanding Neurogenesis

“Neurogenesis” is the term that scientists use to demarcate to the process of the creation of neurons – the principal cells that make up the brain and larger nervous system in the animal kingdom.

To further understand how this process works, we need to understand two important concepts: neural stem cells and the hippocampus.

The hippocampus is an important structure in the brain that is involved in all sorts of central functions, including our emotions, memories, moods, and the process by which we learn new concepts. Until very recently, most researchers had settled on the idea that each individual had a finite cap governing the total number of neurons that he or she would ever have.

However, recent research has proven without a doubt that this was an incorrect assumption, and new ideas and new research would be destined to lead the way into a new theory of neurogenesis.

Over the last half decade, we have come to understand that neurons can be created. And the area of the brain most intimately involved in this process is – you guessed it – the hippocampus.

The hippocampus is precisely how the brain can undergo neurogenesis in a postpartum life context. While certain scientists even decades ago were ahead of the curve and believed this, the scientific community at large was unwilling to accept this idea. But new data has come to light that has moved this theoretical perspective into the spotlight as our base case scenario.

The Endocannabinoid System and Neurogenesis

As we have previously discussed, the endocannabinoid system is a central functional apparatus by which human physiology governs and maintains itself in a number of important capacities. In the brain, the endocannabinoid system has a wide range of important functions, including the functionality of neurotransmitters and brain chemistry.

However, recently, we have come to understand that the endocannabinoid system plays an important role in cellular genesis, including neurogenesis within the brain.

One of the most important developments from a research standpoint has been the emergence of our understanding that there are two forms of administration of cannabinoids that must be appreciated: acute and chronic.

The difference between the two should be relatively obvious. Acute administration of cannabinoids is the process at a specific point in time of exposing the body to a high level of externally provided cannabinoids. Chronic administration of cannabinoids is differentiated by being distributed over a larger period of time and sustained so that the body adapts through its various cycles on a daily, weekly, and monthly basis.

Research thus far conducted has established the fact that, while acute administration of cannabinoids at a level that exposes important endocannabinoid receptors has not shown a particular impact on neurogenesis, chronic exposure to exogenous cannabinoids has had an important impact particularly in animal studies utilizing rats.

What About Deficiency?

Under circumstances where an individual is suffering from a deficiency of cannabinoid exposure, research suggests that acute administration can be important. While this research is sparse at this point, the results so far shown are compelling. Ultimately, the scientific community needs to pick up the baton and run it further down the track.

There is fertile potential in the emerging field of neurogenesis for the role of cannabinoids, but more research must be conducted to firmly establish the pattern of interrelationships to allow us to mobilize it to therapeutic ends for the development and maintenance of more effective neuroscience.

BENEFITS OF CBD

Healing Properties CBD and Addison’s Disease

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Primary adrenal insufficiency, also known as Addison’s disease, is a very rare condition that impacts the adrenal cortex, resulting in a number of very difficult symptoms, including a lack of appetite, lethargy, possible adrenal crisis, loss of weight, and erratic mood.

One of the symptoms noted above – adrenal crisis – is a particularly acute experience that should be treated as a medical emergency. During that adrenal crisis, one may experience a dramatic loss of blood pressure accompanied by dizziness, lower body pain, and fainting spells.

Such an attack can result in death.

Coming to Grips with Addison’s Disease

The adrenal cortex is a rare instance of the word cortex being applied to something that is outside of the brain. In fact, the adrenal cortex is found on the top of the kidneys, and is made of a couple of different glands.

This is part of the HPA, which is an important axis of connected components that regulate many different functions in the body.

One element of this system is known as the endocrine system, which is in charge of various molecular signals in the body, such as hormones. The regulation of this system is critical in a number of different processes that sit at the very core of our physiological functionality.

On the other hand, the adrenal system is in charge of things like our ability to deal with sudden danger – commonly known as the fight or flight system. This is how we respond to highly stressful and highly dangerous situations encountered unexpectedly during daily life. Much of this is dealt with by the pituitary gland, which produces important chemical components that instinctively energize responses in the body.

For those suffering from Addison’s disease, we see it atrophying of this core system. This interrupts the processes that allow us to behave in a manner that our bodies were designed.

Without this properly functioning system we can end up lacking important responses in certain situations while having those responses happen to us in inappropriate situations. But we can also have a number of other symptoms such as those described above.

The role of CBD In Addison’s Disease

It’s certainly true that Addison’s disease is relatively uncommon. However, CBD is an excellent resource for those suffering from this terrible condition.

In our other pieces, we have previously described the importance of the endocannabinoid system and how it is tied throughout the body’s important systems.

Well, as you might have guessed, the endocannabinoid system is also an important part in dealing with Addison’s disease. Because this is such a critical and interconnected system throughout the body, you’ll find that it has a very complex relationships with many different sources of discomfort, malady, and disease. The case of Addison’s disease is no different.

CBD can be an important component in treating and or preventing a case of Addison’s disease because it isn’t impactful element in the functionality of the endocannabinoid system, as we have discussed in our prior pieces. In fact, much anecdotal evidence exists alongside some genuine research by the medical and scientific community to support these contentions.

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BENEFITS OF CBD

The Effects of CBD and Glaucoma

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facts about CBD and Glaucoma

As we discussed the variety of different health conditions that appear to be treatable or preventable through the use of CBD, we must admit to the existence of a spectrum of efficacy. In other words while it appears to have an enormous range of application, there are certain things that it works even better for than others.

One of the best of the bunch is glaucoma.

As the reader is likely aware, glaucoma is a defect with implications for severe damage to an individual’s optic nerve, and thus a failure in the proper functionality of the eye.

Coming to Terms with Glaucoma

While we don’t understand exactly how it’s cause, the most relevant source of serious long-term damage to the optic nerve in cases of glaucoma appears to be hypertension on an intraocular level. In other words,, comes from too much pressure inside of the eye because of too much fluid in between the iris and cornea.

How prevalent is glaucoma? About 2 million suffer from it just in the US. Most of them are around 50 years of age or older by the time we actually see signs of the glaucoma.

The early stage symptomology is relatively inconspicuous. The first thing you deal with in a case of glaucoma’s difficulty seeing out to your periphery – otherwise known as a loss of peripheral vision. If this happens to you, unfortunately I have some bad news: glaucoma is already irreversible at this stage.

This is when we know that there’s already too much pressure directly in the eye and damage is already been done to the optic nerve.

While we don’t fully understand exactly why or how this happens from the outset, the consequences are undeniable.

Here’s how it breaks down: the eye produces something called aqueous humor. No, that’s not a comedy club for fish. It’s actually a fluid it’s meant to sit between the iris and cornea of the eye. But when there’s too much of it, it results in pressure that can damage the optic nerve. It’s also important to understand that this is a very sensitive system.

The optic nerve is actually a highly delicate grouping of nerve tissue and it’s easily damaged. It is a highly delicate instrument. Any alteration leads to irreversible issues with vision.

Can CBD Help?

As we have described, glaucoma is the result of a failure to regulate some delicate balance of some kind of substance somewhere in the body – in this case, the aqueous humor in the eye. What we want to highlight here is that this is a regulatory issue.

While CBD is still on the frontier of its important research development, one thing we have learned for certain at this point is this: CBD is great at regulatory problems.

Why? Because CBD impacts the endocannabinoid system, and the endocannabinoid system is intimately tied into most of the body’s major regulatory systems.

That’s why it’s so good at helping with immune system issues, inflammation issues, pain management, and hormonal balance. These are all important regulatory functions in the body, and ones that the endocannabinoid system is intimately integrated within.

As such, anecdotal and formal research has shown CBD could be a highly valuable tool in the battle against glaucoma. While more research needs to be conducted, we already know that it’s effective, and we already have a pretty good idea why.

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BENEFITS OF CBD

Treatment Option for CBD and Sickle Cell Anemia

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Did you know that scientists aren’t even sure how many people are affected by sickle cell anemia in the world right now? Most people don’t realize that one of the most frequently identified hereditary conditions is in fact sickle cell anemia.

While we don’t know exactly how many people suffer from this difficult condition, we do know that it’s at least millions. Those living in Southwest Asia, the Mediterranean countries, Africa, and India are most at risk.

Coming to Grips with Sickle Cell Anemia

Sickle cell anemia is a common version of the sickle cell disease, as you might guess. The most important and peculiar characteristic that defines this disease is a crescent shape found in red blood cells.

A red blood cell isn’t supposed to be crescent-shaped. Instead, it supposed to be round and flattish, allowing transportation through membranes with tight gaps, which are common throughout the body’s circulatory system.

It is this crescent-shaped or sickle shaped character as well as a rigidity that is responsible for all of the problems that go along with sickle cell disease.

What Causes Sickle Cell Disease?

The cause of sickle cell disease is a gene mutation. Specifically, it is the gene that responsible for hemoglobin production.

Hemoglobin, an important protein found in red blood cells, attaches itself to oxygen molecules to help transport them around the body.

The mutation that causes sickle cell disease is a mutation involved in the production of the shape of red blood cells, resulting in the misshapen, rigid, sickle shaped design that is responsible for the problems that come with this difficult condition.

At the end of the day, the problem that is found with this condition is that of factors involved in causing a difficulty adjusting when the weather is cold, some occasional bouts of dizziness, and a lack of energy.

Diagnosis is actually extremely easy, and most cases of the disease are already detected by the time the baby is born. That said, to know for sure, a doctor will prescribe a blood test diagnosis that will determine precisely whether or not the patient carries the sickle cell abnormality and thus will suffer from effects associated with the disease.

A Solution and a Problem

If you understand more about sickle cell disease, it may not be too surprising to know that case density is greatest in areas where prevalence of malaria is to be found.

You see, the odd shape of red blood cells for individuals with sickle cell disease actually works to repel the spread of malaria throughout the body. Hence, over an even illusionary timeline, sickle cell disease has actually evolved as a defense in areas where malaria is particularly common in individuals are likely to be exposed to it.

In such places, having sickle cell disease actually decreases one’s chances of death, thereby increasing one’s chances of survival and eventual reproduction. This is why the disease has gained traction in certain areas of the world.

How Can CBD Help?

While there are no absolute treatments for sickle cell disease, cannabis and CBD have appeared to make a positive difference in both coping and managing the process that one must endure as a sufferer of sickle cell anemia.

CBD works to aid in the functionality of the immune system as well is the nervous system, thus treating many of the symptoms that are most often experienced by those with this terrible disease.

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