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Cara Therapeutics Inc (NASDAQ: CARA) and Vifor Pharma Announce Approval of KORSUVATM

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Cara Therapeutics Inc (NASDAQ: CARA) and Vifor Pharma have announced that the U.S Food and Drug Administration (FDA) has approved KORSUVA™ (difelikefalin) to treat moderate to severe pruritus associated with chronic kidney disease in adults undergoing haemodialysis. The injection is a first-class kappa opioid receptor (KOR). It targets the peripheral nervous system. The drug’s new use has received priority review from the FDA.

Clinical trials proved the drug’s efficacy 

 According to Derek Chalmers, the CEO and President of Cara Therapeutics, the approval of KORSUVATM is a milestone for the company. It is also a breakthrough for adult patients going through haemodialysis that have moderate to severe pruritus. Cara looks forward to working with Vifor to release the drug in the US in the coming months. He adds that the 10-year commitment of the two companies to their studies made it a possibility.

Abass Hussain, CEO of Vifor Pharma, adds that there is a need for targeted therapy. Vifor believes that the drug could change the way adult patients undergoing dialysis are treated. The company is committed to bringing KORSUVATM into the U.S market as fast as possible through its partnership with Cara.

The drug has received approval as a first-line treatment for adult patients with moderate to severe pruritus due to haemodialysis. The clinical trials have led the two companies to the conclusion that the drug is effective. Researchers during the trial saw significant progress in patients who had reported severe itching. It was also was well tolerated.

The companies filed a New Drug Application filing backed up by positive data from two Phase 3 trials, that is, KALM-1 in the U.S and the global KALM-2. Information presented also included supportive data from 32 other clinical studies.

Licensing and profit-sharing

Cara and Vifor have agreed to an exclusive license to sell the drug in the U.S. Cara will get 60% of the profit, and 40% will go to Vifor in non-Fresenius medical care clinics. The companies are now submitting the required documents to the U.S Centres for Medicare and Medicaid Services (CMS) to ensure patients access the drug and timely reimbursement. Vifor will begin promoting the drug in Q1 2022. Repayment is expected on H1 2022.

*Past performance is not a predictor of future results. All investing involves risk of loss and individual investments may vary. The examples provided may not be representative of typical results. Your capital is at risk when you invest – you can lose some or all of your money. Never risk more than you can afford to lose.By submitting your information you agree to the terms of our Privacy Policy • Cancel Newsletter Any Time.This is a FREE service from Finacials Trend. Signing up for our FREE daily e-letter also entitles you to receive this report. We will NOT share your email address with anyone.
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Nextleaf Solutions Ltd (OTCMKTS: OILFF) Launched New Products Through Medicibis

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Nextleaf Solutions Ltd (OTCMKTS: OILFF) has announced that Glacial Gold Distilled CBD 200 Oil and Distilled CBD 100 Oil will be available through Medicibis, its distribution partner in Quebec.

Distilled CBD 200 Oil has 5700 my CBD per unit, which is the highest in the market. It also has high potency for an ingestible format at an affordable price. Nextleaf uses its patented ingredient processing technology to produce Glacial Gold products.

 The company formulates Glacial Gold distilled oils with a standard CBD dose and organic coconut MCT oil. In addition, Nextleaf is a leafing supplier of oils and values in British Columbia, Canada. The company had managed to land several of its products in the Top 20 SKU in the oils and vapes categories.

Nextleaf sell products through Mendo Medical

Nextleaf sells its products to its Canadian customers through Mendo Medical. Mendo sells its cannabis products online and distributes them throughout the country.

According to the COO and co-founder of Mendo, Jay Schwartz, the company has made it easy to obtain a medical cannabis document and become a member of Mendo. Canadians who want to buy from Mendo can now follow a link on the company’s online platforms and schedule an appointment with a medical professional.

The customers can also have their appointment through video conferencing or a phone call. Furthermore, it takes 24-36 hours for the consumer to get approval from an expert. After this, they can start purchasing Mendo products on the next business day.

The CEO and co-founder of Nextleaf, Paul Pedersen, adds that Mendo’s team has experience worming in Quebec. For this reason, they can increase distribution and growth on the platform. Petersen adds that the company is glad to supply Glacial Gold distilled oils and vapes to Canadian through Mendo Medical.

Cannabis might treat opioid use disorder

Experts have long considered that CBD could be a therapy for opioid use disorder. For this reason, the Food and Drug Administration (FDA) gave UCLA approval for human trials investigating the use of CBD.  The U.S National Institute on Drug Abuse will find the study.

Meanwhile, veterans need a consistent supply of cannabis products to treat chronic Meanwhile pain and PTSD, which companies like Nextleaf provide.

*Past performance is not a predictor of future results. All investing involves risk of loss and individual investments may vary. The examples provided may not be representative of typical results. Your capital is at risk when you invest – you can lose some or all of your money. Never risk more than you can afford to lose.By submitting your information you agree to the terms of our Privacy Policy • Cancel Newsletter Any Time.This is a FREE service from Finacials Trend. Signing up for our FREE daily e-letter also entitles you to receive this report. We will NOT share your email address with anyone.
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Hemp Inc (OTCMKTS: HEMP) Reports on Hemp-based Batteries

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Hemp Inc (OTCMKTS: HEMP) reported on using hemp-based batteries. The company has also detailed how Canadian and American researchers used hemp fiber to create a battery for power tools and cars.

Report details how researchers used hemp

A report by Return to Now explains how the team cooked the woody pulp and made carbon nanosheets out of it. They then used the nanosheets to make supercapacitors. These were just as good or even better than the widely used graphene.

Supercapacitors are for energy storage. While they are commonly in the form of batteries, scientists have had challenges in developing capacitors that are on par with the rate of electronic component evolution.

Although scientists can store energy in many no-hemp batteries, they are typically too heavy. Moreover, they release energy and charge too slowly.

While this information is not new, experts believe further research could expand our knowledge on hemp in 2022.

High Grade Hemp Seed refers to help batteries as supercapacitors. It explains that Lithium-ion batteries can store energy for long periods and release it slowly. However, they cannot release energy quickly. Supercapacitors like hemp batteries can.

Supercapacitors can release all their energy quickly to boost a vehicle essential for an electric car. Despite this, they can’t store energy for a long time. Fortunately, they get preventative energy from braking.

Benefits of a hemp-based battery

According to Dr. David Mitlin,  a lead study author and chemical engineer from Clarkson University, New York, using hemp instead of lithium batteries would make EVs and other devices sustainable. In addition, lithium-ion, which most car manufacturers use to make car batteries, is more expensive than hemp.

Hemp-based batteries hold many other benefits. These include it being cheaper than graphene. Hemp is cheaper to source than graphene as experts could use help waste derive from farmers.  Furthermore, hemp only requires a few months to reach maturity and can grow in various soil types. Graphene, on the other hand, is hard to produce in large amounts.

Hemp batteries also have high conductivity despite cold or hot temperatures. As a result, they can be used in different climates. The battery also has very high conductivity.

*Past performance is not a predictor of future results. All investing involves risk of loss and individual investments may vary. The examples provided may not be representative of typical results. Your capital is at risk when you invest – you can lose some or all of your money. Never risk more than you can afford to lose.By submitting your information you agree to the terms of our Privacy Policy • Cancel Newsletter Any Time.This is a FREE service from Finacials Trend. Signing up for our FREE daily e-letter also entitles you to receive this report. We will NOT share your email address with anyone.
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Kaya Holdings Inc (OTCMKTS: KAYS) Acquires 50% of Medical Cannabis Project in Epidaurus, Greece

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Kaya Holdings, Inc (OTCMKTS: KAYS) recently announced that its majority-owned subsidiary Kaya Farms Greece has agreed with the Medical Cannabis Project in Epidaurus, Greece (“Greek Kaya”) to acquire 50% of the company. 

Kaya Holdings Inc is the first U.S. publicly traded company to own and operate cannabis licenses in all “touch the plant” categories. In addition, this move marks Kaya Holding’s second cannabis venture in the EU nations.

Details of the new site

The new site consists of two connected industrial buildings on 2.8 acres of land. In addition, it has its own independent industrial electrical power center that supplies ample water required to the facility. 

The Greek Kaya Project includes 25,000 SF of indoor cannabis cultivation, a 15,000 square foot EU-GMP extraction and processing facility, and a 10,000 square foot EU-GMP packing area. The site also has ample room for expansion to construct an extra 15,000 square feet.

The project is smaller in size than Thebes, Greece, another of the Company’s projects, aids it to fast track cultivation and processing of its proprietary branded cannabis products. The projects also distribute its products in legal European Union markets as they await enormous legal cannabis demand to emerge before developing a large-scale capacity in Thebes.

The company will leverage its international relationships

Craig Frank, Kaya’s CEO, recently stated that the Company anticipates that this year will be a good one. Its efforts to benefit the European cannabis market have started coming to fruition. He added that the Company strengthened its international relationships substantially in 2021, and it now possesses the network to make bold steps that claim the company’s stake in the global cannabis sector.  

The company intends to develop and cultivate proprietary cannabis brands and distribute them in Greece and other EU markets as authorized by local regulations. The joint venture is awaiting project financing and final license approval from Greek government authorities.

Kaya Holdings, Inc. is an industry veteran that vertically integrated the legal cannabis organizations operating several majority-owned subsidiaries that cultivate, develop and distribute premium medical and recreational cannabis products. The Company develops cannabis products such as oils and extracts, cannabis-infused foods and beverages.

*Past performance is not a predictor of future results. All investing involves risk of loss and individual investments may vary. The examples provided may not be representative of typical results. Your capital is at risk when you invest – you can lose some or all of your money. Never risk more than you can afford to lose.By submitting your information you agree to the terms of our Privacy Policy • Cancel Newsletter Any Time.This is a FREE service from Finacials Trend. Signing up for our FREE daily e-letter also entitles you to receive this report. We will NOT share your email address with anyone.
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