Few people realize that sickle cell anemia is actually one of the most common congenital disorders.
In fact, we don’t even know how many people are affected by SCA worldwide, but the number is expected to be well into the millions. At particular risk are those in sub-Saharan Africa, Southwest Asia, India, and Mediterranean countries.
Understanding Sickle Cell Anemia
Sickle cell anemia is a form of the sickle cell disease, as its name likely suggests. The disease is characterized by a crescent shape for red blood cells. As most readers probably know, red blood cells are the cells in charge of transportation of oxygen around the body.
A healthy, normal red blood cell is generally flattish and round in profile. This design allows them the flexibility to fit through tight gaps as they race around the circulatory system.
For those suffering from sickle cell disease, such cells are sickle shaped as well as highly rigid in a manner that can cause many issues.
It is actually mutation of a gene in charge of production of hemoglobin’s that is at the root cause of sickle cell anemia.
Hemoglobin is a protein in our red blood cells that binds to oxygen for transportation. The mutation involved in sickle cell disease, as noted above, produces sickle shaped, rigid, and ineffective red blood cells.
That’s why those suffering from sickle cell anemia often report dizziness, difficulty adjusting to colder temperatures, and lethargy.
For those dealing with sickle cell anemia, the defective hemoglobin, and the resultant form error and rigidity of the red blood cells, reduces the effectiveness of the cell in the transportation of oxygen. We know that much. However, there is an even bigger problem: this same condition can lead to a blockage in the capillaries as the cells pileup on one another and don’t properly fit through the tight spaces characterizing the distal regions of the circulatory system.
It’s this secondary set of symptomology that really causes the danger for sickle cell disease.
In terms of identifying the condition, because it comes down to genes, many cases are known before birth. However, to establish it for certain, doctors will simply use a blood test. Interestingly, several European countries advise couples to have an abortion when a fetus in utero is known to have this disease.
Eight out of every ten cases of sickle cell anemia occur in sub-Saharan Africa. The reason is an evolutionary one: the sickle shape of the cells actually repels malaria, and malaria is most common in sub-Saharan Africa.
Hence, over great swaths of time, individuals living in an area where a disease like malaria is highly prevalent will have a better chance of surviving and reproducing if there circulatory system is seeded with cells and resistant to the disease.
As for treatment, all we can really do at this point is seek to relieve pain through the use of opioids and morphine. However, obviously these have side effects.
Blood transfusions and bone marrow transplants are also common, but they tend to have their own list of risks and associated side effects.
At this point, there is no cure for sickle cell anemia. Ideal management of the disease will generally lead to a lifespan that is only about three quarters of a normal human lifespan in the developed world.
CBD and Sickle Cell Anemia
As noted above, there are no definite treatments for the disease, but many people have used cannabis and CBD to attempt to cope better and manage the process of dealing with sickle cell anemia.
Research has shown that CBD, in particular, normalizes immune system and nervous system disruptions, which can reduce the impact of the symptoms associated with sickle cell anemia
One recent study showed that mice affected by something similar to sickle cell anemia actually experienced less pain and less inflammation once cannabinoids receptors were properly activated.
For scientists, the conclusions from this study have powerfully shifted our understanding of this disease.
At this point, while CBD is definitely not a cure all for the sickle cell disease and sickle cell anemia, it may become more widely used in such cases and has already shown to be a valuable tool for those suffering from this terrible disease.
BevCanna A Leader In The North American Infused Beverage Sector
Why BevCanna May Already Have Pole Position for the Coming Cannabis Beverage Craze
New Opportunity: BevCanna Enterprises Inc. (CSE:BEV) (OTC:BVNNF)
- Leader/Innovator in Emerging multi-billion-dollar Cannabis-Infused Beverage space
- Recently announced coming transition to full commercial-stage operations in coming months
- Set to become Canada’s largest organic outdoor cannabis cultivator
- World-class bottling facility about to receive full cannabis-infused bev production license
- Launching in California and Canada with Sales ramping in Q3
The big Cannabis-infused product bull market of 2019 didn’t exactly pan out like so many had believed following the landmark US Farm Bill, momentum from regulatory authorities, and a spate of high-profile Fortune 500 JV moves (ie Molson Coors and HEXO, Altria and CRON, Constellation Brands and Canopy, etc) that seemed to suggest the writing was on the wall for this transformational trend to get in gear.
What happens when everyone gets excited about a big investment theme too early? That’s right! A destructive and painful bear market. This has been story for the whole cannabis space for the past year.
However, given a purging in the pot stock space and new regulatory measures now in place for cannabis-infused beverages in Canada and California, the explosive trend in cannabis beverages can now take flight.
We believe two points are key here for investors: 1. Cannabis-infused beverage leadership investments will be far superior to non-beverage plays in the cannabis sector because of the higher barrier to entry in terms of facilities, expertise, and regulatory hurdles, and 2. BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) is likely to emerge as the big speculative winner this year in that niche given a number of inherent advantages and a proactive production ramping process that has already started to take hold.
As the cannabis space heals, BevCanna is supremely positioned to assume a leadership role in a space that is defined more by new adopters than by long-time cannabis consumers. Growth is being driven by new cannabis consumers exploring the marketplace given the expanded legality of cannabis. And new cannabis consumers are, on the margin, more likely to choose new ways of consuming cannabis – ie, many don’t want to smoke it.
According to Brightfield Group researchers, cannabis-infused beverages will represent one of the fastest growing segments of the overall cannabis product complex over the next 10 years. Fior Markets found that the global cannabis beverages market could generate $4.57 billion by 2025. Companies delivering cannabis drinks in Canada in 2020 will be set up for market dominance over the next 5-10 years as the trend takes flight.
BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) shares are perfectly positioned to capitalize on this trend, which makes the company a likely candidate for some M&A chatter as cannabis-infused beverages expand to conquer the North American consumer this year.
BevCanna’s Inherent Advantages
BevCanna Enterprises Inc. (CSE:BEV, OTCMKTS:BVNNF) bills itself as an emerging leader in infused beverage manufacturing. The company develops and manufactures cannabinoid-infused beverages and consumer products for in-house brands and white label clients.
BVNNF has been in development-stage operations since IPO-ing last summer. According to recent company communications, the stage is set for a rapid transformation to full commercial-stage operations, with sales likely to hit full volume in Canadian and California markets starting in Q3 of this year.
The company runs a 40k sq ft HACCP certified manufacturing facility, with a current bottling capacity of up to 210M bottles per annum.
The facility is state-of-the-art, with the capability of producing custom bottle form factors and water-soluble cannabinoids. This opens up an immediately obvious leadership potential for white-label product development to complement the company’s in-house brands.
The company also has access to a 100+ acre outdoor cultivation site with an on-site natural spring aquifer.
The team is also a top-draw, with former leaders at Vega, Mike’s Hard Lemonade, and other top disruptive brands and companies in the functional beverage and wellness markets and highly-regulated markets, as well as veterans from Goldman Sachs, Frito Lay, and General Mills. So, they know how to commercialize into big market opportunities.
In other words, this is a company with a world-class facility and a world-class team. And they will be receiving their cannabis-infused beverage production license very soon (They already have the research and cultivation licenses).
There’s a high regulatory barrier to entry for the cannabis-infused beverage space. That will keep competition suppressed, leaving the big profits to be made those specialist players with the resources, equipment, expertise, and regulatory clearance to dominate this high-growth market niche.
BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) may be the best of breed the publicly traded markets right now among companies that meet all of these criteria. More to the point, the company is on track to have some of the first cannabis-infused beverages on the market as this phase of the cannabis revolution just gets off the ground.
The Company recently announced that it is significantly expanding its manufacturing premises in anticipation of receiving its standard processing license and initiating full-scale commercialization this year.
In other words, they’re about to gain access to a massive and thriving market looking for cannabis-infused beverages. And the company wants to be ready to soak up every dime of potential sales right out of the gate. So these folks, being experienced business leaders, are getting ready to meet that demand with an increased capacity to produce product supplies when the bell rings and the government says “Go!”.
“This expansion is an exciting step for BevCanna,” said John Campbell, Chief Strategy Officer at BevCanna. “We expect to receive our standard processing license imminently, and we’re preparing to initiate full-scale production in the coming months. We’ve seen a fantastic consumer and industry response to the upcoming Canadian beverage market, and this development ensures that we have capacity and full product offerings to fulfil the anticipated demand.”
Just before that, the company announced that it has entered into a definitive joint venture agreement with Mota Ventures Corp. (CSE:MOTA FSE: 1WZ:GR OTC: PEMTF), to exclusively distribute BevCanna’s hemp-derived products in the European market.
That followed the company’s announcement that it is working with partner Nextleaf Solutions Ltd. (Nextleaf) (CSE:OILS, OTCQB:OILFF, FSE:L0MA), to employ their nano-delivery technology in BevCanna’s upcoming lines of cannabis-infused beverages. BevCanna will have the exclusive rights to commercialize this unique technology, giving the company yet another edge as a market leader in white label services.
According to the release, Nextleaf, BevCanna’s exclusive provider of water-soluble cannabinoids, has completed its acquisition of the intellectual property pertaining to the nano-delivery of cannabinoids. The acquisition includes the foundational processing methodology and two water-soluble formulations. Nextleaf intends to seek patent protection around the acquired IP and to partner with BevCanna to develop a new patent family around infused beverages.
“The IP allows consumers to feel the desired effect from cannabis-infused beverages in under 10 minutes,” said John Campbell, Chief Strategy Officer at BevCanna. “We’re eager to commercialize this innovative technology in Canada; and to act as the exclusive beverage commercialization partner, through BevCanna’s branded and white-label cannabis-infused beverages.”
Looking ahead, the company expects to receive its full license imminently, and then begin full commercial operations. In other words, this is the most exciting time to come across this stock: right in front of its most dramatic and market-moving catalysts, including full-licensing, initial product shipment, expanding sales, expanding markets, topline growth, and everything that analysts and investors typically scan for when hunting new speculative opportunities.
Right now, you have a chance at it ahead of that crowd.
One of the key points to make here is the stock’s relative strength. The cannabis equity sector has been destroyed over the past 6-12 months, and many are still in crash mode. At the same time, BVNNF shares show clear evidence of a major accumulation bid likely by smart money working to expand exposure ahead of the coming parade of high-profile catalysts just ahead for the stock.
Shares are sitting above major moving averages, but well-consolidated and ready for a potential next-leg higher if trendline resistance above the $0.33-0.35 area is cleared. This breakout would be very well supported given the nature of the stock’s basing process, which came on rising volume and bullish divergence on MACD.
About BevCanna Enterprises
BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) develops and manufactures cannabinoid-infused beverages and consumer products for in-house brands and white label clients.
With decades of experience creating, branding and distributing iconic brands that have resonated with consumers on a global scale, the team demonstrates an expertise unmatched in the emerging cannabis beverage category.
Based in British Columbia, Canada, BevCanna has a 292-acre outdoor cultivation site in the Okanagan Valley and the exclusive rights to a pristine spring water aquifer, access to a world-class 40,000-square-foot, HACCP certified manufacturing facility, with a current bottling capacity of up to 210M bottles per annum.
BevCanna’s vision is to be a global leader in infused innovations.
- BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) is about to receive its full cannabis-infused production license, which will allow the company to start ramping up full commercial operations as a likely leadership name in the Cannabis Bev space
- BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) has a small trading float of just 38.3M, which suggests the stock could launch higher on any additional influx of interest.
- BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) has a world-class facility and team, positioning the company as a dominant entity in the relatively closed loop of Canadian Cannabis-infused beverage producers
- BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) has been demonstrating clear relative strength, outperforming peers in the cannabis space by a wide margin during the recent tailspin in the pot stock sector.
- BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) just recorded a MACD Bullish divergence on a rising-volume base, suggesting a technical change in trend with upside breakout potential above.
- BevCanna Enterprises Inc. (OTCMKTS:BVNNF) (CSE:BEV) is set to start clocking big sales growth over coming months with innovative in-house branded products and a thriving white-label business targeting Canada and California
To circle back around, the cannabis bear market has come and possibly gone. And now it’s time to start picking through the rubble because there are probably some life-altering investment opportunities just lying around the floor right now in this space.
Our thesis remains: 1. Cannabis-infused beverages will offer more growth with less competition if you stick to best-of-breed plays, and 2. BevCanna, with its world-class state-of-the-art massive facility and blue-chip team with leadership experience in major markets across similar sectors, is about to gain its fully licensed access to that marketplace. And when that happens, BVNNF will be that best-of-breed name in the cannabis-infused beverage marketplace.
Benefits of CBD You Must Know
CBD has been with us for hundreds of years, used by ancients as a natural remedy for a lot of common ailments. It is only one of more than a hundred chemical compounds found in the hemp or cannabis plant. CBD-infused products like CBD oil, CBD softgel capsules, CBD cream, and others have become appealing alternatives for people seeking relief.
CBD oil gets extracted from the hemp plant, then diluted with a carrier oil such as hemp seed or coconut oil. It’s fast becoming popular in wellness and health circles as an option in the treatment of chronic pain, anxiety, and other symptoms brought about by certain disorders.
The benefits of CBD
Because of CBD’s vast variety and reach, it’s used in various mediums of treatment. Like any other medication introduced to the body, your body needs time for adjustment. CBD can help with symptoms but don’t expect overnight results.
It’s generally recommended to use CBD between 30 to 60 days before witnessing any significant impact. If you decide to try CBD, here are some benefits to look forward to:
• Pain relief
Research has shown that CBD has analgesic properties. This means it’s effective for pain relief. When introduced into the body, CBD can impact the endocannabinoid system’s receptor activity resulting in the reduction of inflammation and the interaction with neurotransmitters.
• Stress relief
In this modern age, many people have experienced feeling overworked or over-booked and this affects their abilities to prioritize through the chaos. In simpler words, they feel stressed.
This is where CBD oil can help as using it can ease the anxieties and worries of everyday life. When used, CBD can calm the nerves which, in turn, allows us to focus more on the tasks at hand.
• Improve sleep
CBD may support our need for a deeper and more restful sleep by reducing chronic anxiety, pain, and the other challenges which prevent us from falling into a deep sleep. Its use can diminish REM sleep disorder too. REM during deep sleep paralyzes the body. This inhibits physical reactions to dreams.
• May help reduce depression and anxiety
Two of the most common mental health problems plaguing the world today are depression and anxiety, both of which can have a devastating impact on one’s health and well-being. Many have attested that the use of CBD oil as effective in the treatment of these disorders. Many are now showing interest in CBD as a natural approach to get back a semblance of normalcy in their lives.
CBD also has anti-depressant properties and these have been linked to its ability to act on the brain’s serotonin receptors, a neurotransmitter compound that regulates social behavior and mood.
• Improve the health of your skin
Today, we find so many lotions, body butter, and hydrating products available in drugstores but are these the right products to reach the moisture levels the body thirsts for? Maybe, but a sure option that can quench such thirst is CBD oil or CBD cream. This is a powerful topical which can help the skin maintain optimal skin moisture.
• It’s non-addictive
Another great quality of CBD is that it’s non-addictive. This means you can keep using the same dose in your treatment without worrying about feeling craving for more. As a matter of fact, the more you use it, the better the results. The body doesn’t build up a tolerance to CBD.
Speak with your doctor about using CBD
There’s continuing research on CBD’s potential role in alleviating pain and other symptoms of common health issues. It might even end up as a natural alternative in the treatment of pain. As research goes on, expect the discovery of new therapeutic and medical uses for this compound.
There’s much more to discover about the safety and efficacy of CBD products. But based on the most recent studies, it’s suggested that CBD may provide a powerful and safe treatment for several prevailing health issues. This is especially true if you purchase your CBD products from high-quality manufacturers like Greenleaf Farms.
What Works Best for Treating Pain with CBD Tincture, Soft gels or Creams? #CBD Tincture #Best All Organic CBD Cream
Cannabidiol (CBD) products such as oils and topicals have become a popular natural remedy for pain. While research is still underway, first-person accounts of the benefits are taking the world by storm.
New products are popping up in every direction you look from CBD oil and CBD tinctures to CBD cream and CBD soft gel capsules. So, no matter your preference, there is a form of CBD to help you treat your pain. Treating pain and inflammation is part of the many benefits that CBD offers the user. Let’s take a deeper look into CBD and pain:
What is CBD and will it make me high?
Many people are skeptical of using CBD as a remedy because of the connotations that come with using a compound that comes from the cannabis or hemp plant. In fact, CBD is the non-intoxicating compound of the cannabis plant and will not make you ‘high’ as if you were smoking marijuana.
The more well-known compound of the plant, THC (tetrahydrocannabinol) is what creates the high. Some CBD oils carry trace amounts (less than 0.3%) of THC. However, oils derived from hemp rather than cannabis do not contain any THC and these are legal in all 50 states across the USA.
How CBD works to reduce pain
When it comes to CBD and pain, this affects the endocannabinoid system in the human body. The endocannabinoid system creates endocannabinoids (its own cannabinoids). The system receives and translates signals from the endocannabinoids and any cannabinoids from CBD products throughout the body.
The endocannabinoid system regulates a variety of functions in the human body. These include immune system responses, sleep and most notably, pain. While CBD does not directly affect the endocannabinoid system according to available research, it does initiate the activation or inhibitions of certain compounds in the body.
CBD in the body can cause a reduction in the absorption of anandamide, a neurotransmitter that helps to regulate pain. Thus, CBD will cause the body to absorb less anandamide, increasing levels in the bloodstream, leading to relief from pain.
The effects of CBD on inflammation to treat pain
Inflammation is the body’s protective response against harmful stimuli. Inflammation is often accompanied by pain, redness and swelling. By treating the cause of the inflammation, you can relieve the pain you might be feeling.
This is one of the most popular ways that CBD is being used as a natural alternative remedy. Since inflammation is one of the body’s immune responses, it is regulated by the endocannabinoid system. So, once again, CBD interacts with neuroreceptors in the body to deliver an anti-inflammatory effect.
By reducing areas of inflammation in the body, CBD can, therefore, help to relieve the pain caused by inflammation. Sometimes the body triggers inflammation when there is no harm done to the body, such as in the case of many autoimmune diseases. CBD oil can greatly help remedy the symptoms of these diseases.
Finding quality CBD products
When using CBD products to relieve pain, you want to find a high-quality CBD product. Be sure to check the details of the oil, tincture or topical that you intend to buy. You want to look for information such as the THC percentage and ensure it is a hemp-derived CBD (especially if you live in a state that has not yet legalized marijuana).
Purchasing your CBD products from a trusted supplier like Greenleaf Farms will ensure that you are receiving a high-quality product. Their hemp is grown under the perfect conditions with no pesticides or herbicides used.
When purchasing from a trusted supplier, it generally comes with the guarantee that you are receiving a pure and authentic CBD to treat and relieve your pain and inflammation. You can also rest easy knowing that your CBD product has been produced with care and your health in mind.